CAL AMSTERDAM – Weed users nearly 25% more likely to need emergency care and hospitalization “Our study demonstrates that the use of this substance is associated with serious negative outcomes, specifically, ED emergency department visits and hospitalizations” 1-800-662-HELP

(CNN) Using recreational marijuana is associated with a higher risk of emergency room care and being hospitalized for any reason, a new study has found.

“Cannabis use is not as benign and safe as some might think,” said study author Nicholas Vozoris, assistant professor and clinician investigator in the division of respirology at the department of medicine at the University of Toronto.

“Our study demonstrates that the use of this substance is associated with serious negative outcomes, specifically, ED (emergency department) visits and hospitalizations,” Vozoris said in an email.

Significant risk of hospitalization.

The study, published Monday in the journal BMJ Open Respiratory Research, looked at national health records data for over 30,000 Ontario, Canada, residents between the ages of 12 and 65 over a six-year period.

When compared with people who did not use marijuana, cannabis users were 22% more likely to visit an emergency department or be hospitalized, the study revealed.

Respiratory problems from smoking weed was the second leading reason users seek emergency care, the study found.

The finding held true even after adjusting the analysis for over 30 other confounding factors, including other illicit drug use, alcohol use and tobacco smoking.

“Physical bodily injury was the leading cause of emergency department visits and hospitalizations among the cannabis users, with respiratory reasons coming in a close second,” Vozoris said.

Marijuana smokers had higher blood and urine levels of several smoke-related toxins such as naphthalene, acrylamide and acrylonitrile than nonsmokers, a 2021 study found. Naphthalene is associated with anemia, liver and neurological damage, while acrylamide and acrylonitrile have been associated with cancer and other health issues.

Another study done last year found teenagers were about twice as likely to report “wheezing or whistling” in the chest after vaping marijuana than after smoking cigarettes or using e-cigarettes.

Growing body of research.

A number of studies have shown an association between marijuana use and injury, both physical and mental.

Marijuana may make sleep worse, especially for regular users, study finds

Heavy use of marijuana by teens and young adults with mood disorders — such as depression and bipolar disorder — has been linked to an increased risk of self-harm, suicide attempts and death, according to a 2021 study.

Another 2021 study found habitual users of cannabis, including teenagers, are increasingly showing up in emergency rooms complaining of severe intestinal distress that’s known as “cannabis hyperemesis syndrome,” or CHS.

The condition causes nausea, severe abdominal pain and prolonged vomiting “which can go on for hours,” Dr. Sam Wang, a pediatric emergency medicine specialist and toxicologist at Children’s Hospital Colorado, told CNN in a prior interview.

A review published earlier this year looked at studies on over 43,000 people and found a negative impact of tetrahydrocannabinol or THC, the main psychoactive compound in cannabis, on the brain’s higher levels of thinking.

For youth, this impact may “consequently lead to reduced educational attainment, and, in adults, to poor work performance and dangerous driving. These consequences may be worse in regular and heavy users,” coauthor Dr. Alexandre Dumais, associate clinical professor of psychiatry at the University of Montreal told CNN in a prior interview.

At a time when “health care systems are already stretched thin around the world following the Covid pandemic and with difficult economic times … cannabis use is on the rise around the world,” Vozoris said.

“Our study results should set off ‘alarm bells’ in the minds of the public, health care professionals, and political leaders,” he said in his email.

https://www.cnn.com/2022/06/27/health/marijuana-emergencies-hospitalization-study-wellness/index.html

CAL AMSTERDAM – Brain scans could help police detect cannabis impairment in drivers – Driving under the influence of psychoactive drugs is a serious offense and a major catalyst for vehicle-related accidents.

Driving under the influence of psychoactive drugs is a serious offense and a major catalyst for vehicle-related accidents. In order to detect irresponsible drivers and sanction them, law enforcement officers employ various tools such as breath analyzers to detect alcohol in a person’s system or rapid drug tests that can respond to specific markers for cocaine, marijuana, and other drugs.

In the not-so-distant future, road checks could also employ mobile brain scanners that detect particular patterns of neural activity associated with intoxication. Scientists explain how this might work for cannabis impairment in a new study.

The alcohol content in the blood is closely related to alcohol-related impairment. Even though a breathalyzer indirectly measures the amount of alcohol in one’s breath, a measurement on the handheld device over a certain threshold of intoxication is very closely correlated with the person’s genuine inability to perform well on the road.

There are also breath tests for THC, the main psychoactive ingredient in cannabis, but they’re not reliable for quantitative analyses. They just tell you if someone used marijuana recently, not how high they actually are. Prosecuting someone who legally used marijuana the night prior due to having THC detected in their breath the next morning is neither fair nor productive for law enforcement whose resources and man hours are stretched thin as they are.

In the United States, there are 18 states, along with Washington D.C. and Guam, that have legalized the recreational use and sale of marijuana. With more states planning similar legislative changes, there is now an important need for developing technological solutions that distinguish between impairment and mild intoxication with THC.

Unlike alcohol, a person’s concentration of THC in the body does not correspond well to functional impairment. People who use cannabis very often quickly develop tolerance and don’t have their driving impaired despite the high levels of THC in their system. Furthermore, THC’s metabolites — the byproducts of THC after the body’s metabolism breaks down the drug — can last in the bloodstream for weeks after cannabis use, well beyond the period one could be deemed intoxicated.

Testing strips or breath analyzers can only tell you if a person used marijuana, but not how much, how recently, or how intoxicated the user truly is. This is why researchers at the Massachusetts General Hospital have developed a noninvasive brain imaging procedure that can reliably identify cannabis users whose performance is impaired in real-time.

For their study, 169 volunteers who use cannabis underwent functional near-infrared spectroscopy (fNIRS) — a technique that measures blood oxygenation changes similar to fMRI, based upon the changes in absorption of light emitted by sources onto the surface of the head and measured by detectors — before and after receiving either oral THC or a placebo.

Those who reported feeling intoxicated after being given oral THC also showed an increased oxygenated hemoglobin concentration (HbO) — a type of neural activity signature from the prefrontal cortex region of the brain – compared to those who reported low or no intoxication. Although the same dose was given to all volunteers, there was a very wide range of impairment measured by the researchers, from very mild intoxication to obvious impairment, underscoring the unreliableness of using THC in the blood or oral fluid to identify impairment.

“Identification of acute impairment from THC intoxication through portable brain imaging could be a vital tool in the hands of police officers in the field,” said A. Eden Evins, MD, MPH, founding director of the Center for Addiction Medicine and senior author of the new study. “The accuracy of this method was confirmed by the fact impairment determined by machine learning models using only information from fNIRS matched self-report and clinical assessment of impairment 76 percent of the time.”

The research did not assess the practicality of using this method for assessing impaired driving, but it’s easy to see how this could be useful to law enforcement. There are cheap, mobile fNIRS devices that can be incorporated into a headband or cap and thus can be quickly set up by an officer to distinguish between cannabis impairment and simple exposure.

But it might take a while before you see brain scanners on the roadside. Besides the technical challenges, there are also important privacy concerns that need to be addressed whenever dealing with such sensitive data as someone’s brain activity.

“Companies are developing breathalyzer devices that only measure exposure to cannabis but not impairment from cannabis,” says Gilman. “We need a method that won’t penalize medical marijuana users or others with insufficient amounts of cannabis in their system to impair their performance. While it requires further study, we believe brain-based testing could provide an objective, practical and much needed solution.”

The findings appeared in the journal Neuropsychopharmacology.

CAL AMSTERDAM – Costa Mesa’s First Cannabis Dispensaries Receive Approval To Set Up Shop – Welcome to “Stoner Nation”

The Costa Mesa planning commission approved Tustin-based Culture Cannabis Club and Costa Mesa-based Vertical Four to be the city’s first cannabis retail dispensaries.

The Culture Cannabis Club store will be stationed at 2301 Newport Boulevard, while the Vertical Four shop will set up shop at 1990 Harbor Boulevard.

Santa Ana, the only other Orange County city to allow cannabis retail shops, has 27 dispensaries. The city has received over $30 million from cannabis sales taxes since it approved cannabis shops for operation in 2017.

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